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Signal Transducers and Activators of Transcription (STATs)
1. DNA Complex of STAT-1
2. N-terminal Domain of STAT-4
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Xiaomin Chen, Uwe Vinkemeier, Yanxiang Zhao, David Jeruzalmi,
James E. Darnell, Jr. and John Kuriyan
STAT-1 DNA Complex,
Pre-release coordinates
Note: Coordinates available here at this web site are for a STAT-1 dimer
on an 18pb DNA, generated from one monomer in the asymmetric unit using
a crystallographic 2-fold operator.
Coordinates for the STAT-1 DNA complex will also be available from the Protein
Databank:
PDB Coordinate file: 1bf5
PDB Structure Factor file: r1bf5sf
Images:
Crystals of STAT-1 DNA Complex
(Fig 2A) 
(Fig 2B)
Other views of STAT-1 DNA
Complex
(Fig 3) 
(Fig 4C)
(Fig 4D) 
(Fig 5A)
(Fig 5B) 
(Fig 6)
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N-Terminal Domain of STAT-4
Vinkemeier, U., Moarefi, I., Darnell, J. E., Jr., and Kuriyan, J. (1998).
Structure of the amino-terminal protein interaction domain of STAT-4.
Science 279, 1048-1052.
Vinkemeier, U., Cohen, S. L., Moarefi, I., Chait, B. T., Kuriyan, J., and
Darnell, J. E. J. (1996).
DNA binding of in vitro activated Stat1a, Stat1b and truncated Stat1:
interaction between NH2-terminal domains stabilizes binding of two dimers
to tandem DNA sites.
EMBO J., 15, 5616-5626.
Crystals of STAT-1 DNA Complex
(Fig 2A) 
(Fig 2B)
Other views of STAT-1 DNA
Complex
(Fig 3) 
(Fig 4C)
(Fig 4D) 
(Fig 5A)
(Fig 5B) 
(Fig 6)
