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Structure of Ras complexed with the Ras exchange factor region of the Son of Sevenless protein

Boriack-Sjodin, P. A., Margarit, S. M., Bar-Sagi, D., and Kuriyan, J. (1998). The structural basis of the activation of Ras by Sos. Nature 394, 337 - 343.

Coordinates: (PDB Code: 1BKD)


Crystals of the Ras-Sos complex

(Fig 1) (Fig 2a)

(Fig 2b) (Fig 3)

(Fig 4 ab) (Fig 4c)

(Fig 5ab) (Fig 5cd)

Fig 6 - N-domain interactions

Switch 1 interactions

Footprint of Ras on Sos